Article

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory study

2019-10-05

Abstract excerpt

<h4>Background</h4> Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome sequencing (WGS) has emerged as a ‘one-stop’ test for epidemiological and predictive AST results. Few published comparisons exist for the myri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f476e9e5-e064-5633-ba92-a367cf0b8609
DOI: 10.1101/793885

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory studyDOI 10.1101/793885Read

Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus on Escherichia coli.Semantic proximity Read

Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus on <i>Escherichia coli</i>Semantic proximity Read

Clinical implementation of routine whole-genome sequencing for hospital infection control of multi-drug resistant pathogensSemantic proximity Read

Whole-genome sequencing to control antimicrobial resistanceSemantic proximity Read

One Day in Denmark: Comparison of Phenotypic and Genotypic Antimicrobial Susceptibility Testing in Bacterial Isolates From Clinical SettingsSemantic proximity Read

Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistanceSemantic proximity Read

Rapid whole genome characterization of antimicrobial-resistant pathogens using long-read sequencing to identify potential healthcare transmission.Semantic proximity Read

Harmonisation of in-silico next-generation sequencing based methods for diagnostics and surveillanceSemantic proximity Read

Influence of Sequencing Technology on Pangenome-level Analysis and Detection of Antimicrobial Resistance Genes in ESKAPE PathogensSemantic proximity Read

Rapid Whole Genome Characterization of High-Risk Pathogens Using Long-Read Sequencing to Identify Potential Healthcare TransmissionSemantic proximity Read

Validation and Implementation of CLIA-Compliant Whole Genome Sequencing (WGS) in Public Health LaboratorySemantic proximity Read

Real-time Nanopore de novo assembly of ESKAPE pathogens: Implications for antibiotic stewardshipSemantic proximity Read