Article

Integrated Bioinformatics Analysis of PALB2 Reveals Expression Patterns, Molecular Interactions, and Prognostic Significance in Breast Cancer

2026-07-23

Abstract excerpt

<h4>Background</h4> Partner and Localizer of BRCA2 (PALB2) is a key tumor suppressor gene involved in homologous recombination-mediated DNA repair through its interactions with BRCA1 and BRCA2. Germline alterations in PALB2 have been associated with hereditary breast cancer risk; however, its broader molecular role in breast cancer progression and prognosis requires further investigation. <h4>Methods</h4> A comp...

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Literature Corpus work: 9f716561-9676-52db-9317-d684b349ef81
DOI: 10.64898/2026.07.19.739427

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