Article

Microglia-to-neuron signaling increases lipid droplet metabolism, enhancing neuronal network activity

2025-08-03

Abstract excerpt

Microglia regulate neuronal circuit plasticity. Disrupting their homeostatic function has detrimental effects on neuronal circuit health. Neuroinflammation contributes to the onset and progression of neurodegenerative diseases, including Alzheimers disease, with several microglial activation genes linked to increased risk for these conditions. Inflammatory microglia alter neuronal excitability, inducing metabolic...

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Literature Corpus work: 9f5e0d30-d99a-5dfc-958a-3d2330e7b4bd
DOI: 10.1101/2025.08.03.668224

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