Article

A comparative study of neuroendocrine heterogeneity in SCLC and NBL

2022-11-18

Abstract excerpt

Lineage plasticity has long been documented in both small cell lung cancer (SCLC) and neuroblastoma (NBL), two clinically distinct neuroendocrine (NE) cancers. In this study, we quantified the NE features of cancer as NE scores and performed a systematic comparison of SCLC and NBL. We found NBL and SCLC cell lines have highly similar molecular profiles and shared therapeutic sensitivity. In addition, NE heterogene...

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Literature Corpus work: 9e9dd244-d281-57fb-a682-dd66b1098143
DOI: 10.1101/2022.11.17.516959

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