Article

Regulation of the human α globin gene cluster in transgenic mice

2001-01-01

Abstract excerpt

Our understanding of ɑ and ß globin gene regulation has been advanced by the development of transgenic mouse technology. Major regulatory elements of both gene clusters have been identified. Extensive studies have shown that the genes, although co-ordinately expressed, differ in their regulation. Transgenic mice containing the ß locus control region (ßLCR) and the ß globin genes produce high level, developmentally...

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Literature Corpus work: 9e8ec25a-eb9a-55ba-8206-331f36ffcafb
DOI: 10.21954/ou.ro.0000f9a8

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