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Article

Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.

Blood - 15 Nov 2002

Anguita Eduardo, Sharpe Jacqueline A, Sloane-Stanley Jacqueline A, Tufarelli Cristina, Higgs Douglas R, Wood William G

Abstract excerpt

Natural deletions of the region upstream of the human alpha-globin gene cluster, together with expression studies in cell lines and transgenic mice, identified a single element (HS -40) as necessary and perhaps sufficient for high-level expression of the alpha-globin genes. A similar element occupies the corresponding position upstream of the mouse (m) alpha-globin genes (mHS -26) and was thought to have similar...

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PMID: 12393394
DOI: 10.1182/blood-2002-05-1409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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