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Article

Definition of transcriptional promoters in the human beta globin locus control region.

Journal of molecular biology - 1 Nov 2002

Routledge S J E, Proudfoot N J

Abstract excerpt

Our previous studies on the human beta globin gene cluster revealed the presence of intergenic transcripts throughout the locus, and demonstrated that transcription of the locus control region (LCR) initiates within an ERV9 endogenous retroviral long-terminal repeat (LTR) upstream of DNase I hypersensitive site 5. We show, using a combination of assays, that there are additional sites of transcription initiation...

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Identifiers

PMID: 12419253
DOI: 10.1016/s0022-2836(02)01011-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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