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Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features

2021-10-21

Abstract excerpt

<title>Abstract</title> <p>Tumor tissue of origin (TOO) is an important factor for guiding treatment decisions. However, TOO cannot be determined for ~3% of metastatic cancer patients and are categorized as cancers of unknown primary (CUP). As whole genome sequencing (WGS) of tumors is now transitioning from the research domain to diagnostic practice in order to address the increasing demand for biomarker detecti...

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Literature Corpus work
9e557e75-fd6f-5cce-9b58-22b1ad13dd54
DOI
10.21203/rs.3.rs-956886/v1
Open publication

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Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation featuresDOI 10.21203/rs.3.rs-956886/v1
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