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CUPiD: A cfDNA methylation-based tissue-of-origin classifier for Cancers of Unknown Primary

2023-12-26

Abstract excerpt

<title>Abstract</title> <p>Cancers of Unknown Primary (CUP) remains a diagnostic and therapeutic challenge due to biological heterogeneity and poor responses to standard chemotherapy. Predicting tissue-of-origin (TOO) molecularly could help refine this diagnosis, with tissue acquisition barriers mitigated via liquid biopsies. However, TOO liquid biopsies have yet to be explored in CUP cohorts. Using publicly avai...

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Literature Corpus work
085baa14-04d7-532e-bb2f-9e9e9c3431fd
DOI
10.21203/rs.3.rs-3758456/v1
Open publication

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