Article

A deep learning system can accurately classify primary and metastatic cancers based on patterns of passenger mutations

2017-11-05

Abstract excerpt

In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of the time a cancer patient presents with metastatic tumour and no obvious primary. Challenges also arise when distinguishing a metastatic recurrence of a previously treated cancer from the emergence of a new one. Here we train a deep learning classifier to predict cancer type bas...

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Literature Corpus work: 98c496d1-cdd2-5740-84a9-f0b161905127
DOI: 10.1101/214494

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