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Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type

18 Jan 2021

Abstract excerpt

Cancer of Unknown Primary (CUP) occurs in 3-5% of patients when standard histological diagnostic tests are unable to determine the origin of metastatic cancer. Typically, a CUP diagnosis is treated empirically and has very poor outcomes, with median overall survival less than one year. Gene expression profiling alone has been used to identify the tissue of origin but struggles with low neoplastic percentage in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33465745
DOI: 10.1016/j.tranon.2021.101016

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