Article

Estimating and visualising multivariable Mendelian randomization analyses within a radial framework

2023-04-04

Abstract excerpt

<h4>Background</h4> Multivariable Mendelian randomization (MVMR) is a statistical approach using genetic variants as instrumental variables to estimate direct causal effects of multiple exposures on an outcome simultaneously. In univariable MR findings are typically illustrated through plots created using summary data from genome-wide association studies (GWAS), yet analogous plots for MVMR have so far been unavai...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9e3ba4f8-f6b2-5f3a-83e2-89dcfb10fd16
DOI: 10.1101/2023.04.04.23288134

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Estimating and visualising multivariable Mendelian randomization analyses within a radial frameworkDOI 10.1101/2023.04.04.23288134Read

Estimating and visualising multivariable Mendelian randomization analyses within a radial framework.Semantic proximity Read

Improving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regressionSemantic proximity Read

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression.Semantic proximity Read

Mendelian Randomization Studies in Atherosclerotic Cardiovascular DiseasesSemantic proximity Read

Testing the principles of Mendelian randomization: Opportunities and complications on a genomewide scaleSemantic proximity Read

Mendelian randomization for cardiovascular diseases: principles and applicationsSemantic proximity Read

Mendelian Randomization.Semantic proximity Read

MRanalysis: a comprehensive online platform for integrated, multimethod Mendelian randomization and associated post-GWAS analyses.Semantic proximity Read

MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data.Semantic proximity Read

MR-Clust: Clustering of genetic variants in Mendelian randomization with similar causal estimatesSemantic proximity Read

Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumptionSemantic proximity Read

Mendelian randomization to assess causal effects of blood lipids on coronary heart disease: lessons from the past and applications to the future.Semantic proximity Read