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Article

MRanalysis: a comprehensive online platform for integrated, multimethod Mendelian randomization and associated post-GWAS analyses.

GigaScience - 6 Jan 2025

Xing Abao, Cai Tiantian, Du Haofan, Li Zhifan, Ng Hoiman, Li Junrong, Jiang Guanmin, Chen Lijun, Li Kefeng

Abstract excerpt

BACKGROUND: Mendelian randomization (MR) is a powerful epidemiological method for inferring causal relationships between exposures and outcomes using genome-wide association study (GWAS) data. However, its adoption is limited by inconsistent data formats, lack of standardized workflows, and the need for programming expertise. To address these challenges, we developed MRanalysis, a user-friendly, web-based...

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PMID: 41124022
DOI: 10.1093/gigascience/giaf131
PMCID: PMC12616851

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