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Article

Mendelian Randomization.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Grover Sandeep, Del Greco M Fabiola, Stein Catherine M, Ziegler Andreas

Abstract excerpt

Confounding and reverse causality have prevented us from drawing meaningful clinical interpretation even in well-powered observational studies. Confounding may be attributed to our inability to randomize the exposure variable in observational studies. Mendelian randomization (MR) is one approach to overcome confounding. It utilizes one or more genetic polymorphisms as a proxy for the exposure variable of...

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PMID: 28980266
DOI: 10.1007/978-1-4939-7274-6_29

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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