Article
Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression.
International journal of epidemiology - 1 Aug 2018
Bowden Jack, Spiller Wesley, Del Greco M Fabiola, Sheehan Nuala, Thompson John, Minelli Cosetta, Davey Smith George
Abstract excerpt
Background: data furnishing a two-sample Mendelian randomization (MR) study are often visualized with the aid of a scatter plot, in which single-nucleotide polymorphism (SNP)-outcome associations are plotted against the SNP-exposure associations to provide an immediate picture of the causal-effect estimate for each individual variant. It is also convenient to overlay the standard inverse-variance weighted (IVW)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
