Article
Analysis of the impact of genetic variation on human gene expression.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Grundberg Elin, Kwan Tony, Pastinen Tomi M
Abstract excerpt
Interindividual variation in gene expression has been convincingly shown to be controlled, in part, by genetic differences. Determining the architecture of genetic variation, the underlying gene expression may allow deeper insight into complex phenotypes, such as differences in disease susceptibility. Mapping genetic variants accounting for expression phenotypes in human cell and tissue panels has rapidly...
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