Article

Functional analysis of the epilepsy gene <i>Pcdh19</i> using a novel conditional GFP-reporter mouse model

2024-03-14

Abstract excerpt

PCDH19 is a cell adhesion molecule belonging to the delta2-protocadherin subfamily that plays a critical role in brain development, neuronal migration, synaptic organisation, and neural circuit formation. Mutations in PCDH19 cause PCDH19-clustering epilepsy, an infantile-onset disorder characterized by seizures and intellectual disabilities. Despite the increasing development of constitutive cellular and murine m...

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Literature Corpus work: c87d01c9-d221-514d-85c5-228ebf05da00
DOI: 10.1101/2024.03.14.584898

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