Article
Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation.
Journal of neurochemistry - 1 Mar 2012
Lobas Mark A, Helsper Lindsey, Vernon Claire G, Schreiner Dietmar, Zhang Yong, Holtzman Michael J, Thedens Daniel R, Weiner Joshua A
Abstract excerpt
The choroid plexus (CP) epithelium develops from the ependyma that lines the ventricular system, and plays a critical role in the development and function of the brain. In addition to being the primary site of CSF production, the CP maintains the blood-CSF barrier via apical tight junctions between epithelial cells. Here we show that the 22-member γ-protocadherin (γ-Pcdh) family of cell adhesion molecules, which...
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