Article

Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated By <i>Cis</i> Noncoding Mutations

2019-06-19

Abstract excerpt

<h4>Summary</h4> Identifying cancer-relevant mutations in noncoding regions is extremely challenging due to the large numbers of such mutations, their low levels of recurrence, and the general difficulty in interpreting their impact. To uncover genes that are dysregulated due to somatic mutations in cis , we build upon the concept of differential allele-specific expression (ASE) and introduce methods to identif...

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Literature Corpus work: 9ba11b3e-77cb-5e76-b22f-8771e9ce3c8a
DOI: 10.1101/675462

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