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Non-coding mutations reveal cancer driver cistromes in luminal breast cancer

2021-05-31

Abstract excerpt

Whole genome sequencing of primary breast tumors enabled the identification of cancer driver genes 1,2 and non-coding cancer driver plexuses from somatic mutations 3–6 . However, differentiating driver and passenger events among non-coding genetic variants remains a challenge to understand the etiology of cancer and inform delivery of personalized cancer medicine. Herein, we reveal an enrichment of non-coding mu...

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Literature Corpus work
5a912efc-9202-5954-905a-7f47749d4498
DOI
10.1101/2021.05.29.446210
Open publication

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Non-coding mutations reveal cancer driver cistromes in luminal breast cancerDOI 10.1101/2021.05.29.446210
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