Article

Acquired Amphotericin B Resistance Attributed to a Mutated <i>ERG3</i> in <i>Candidozyma auris</i>

2025-04-03

Abstract excerpt

First identified in 2009, Candidozyma auris (formerly Candida auris ) is an emerging multidrug resistant fungus that can cause invasive infections with a crude mortality rate ranging from 30-60%. Currently, 30-50% of C. auris isolates are intrinsically resistant to amphotericin B. In this work, we characterized a clinical case of acquired amphotericin B resistance using whole genome sequencing, a large-scale ph...

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Literature Corpus work: 9b7ee7a9-6ffb-5ae5-a610-afeea8c251d5
DOI: 10.1101/2025.03.30.646105

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