Article

A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture

2023-10-04

Abstract excerpt

Mitochondrial cristae architecture is crucial for optimal respiratory function of the organelle. Cristae shape is maintained in part by the mitochondrial inner membrane-localized MICOS complex. While MICOS is required for normal cristae morphology, the precise mechanistic role of each of the seven human MICOS subunits, and how the complex coordinates with other cristae shaping factors, has not been fully determine...

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Literature Corpus work: 9b3da56e-6d6f-595d-8be9-3447251ac0e7
DOI: 10.1101/2023.10.03.560745

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