Article

Integrative structure determination of a human mitochondrial contact site and cristae organizing system (MICOS) sub-assembly

2026-07-22

Abstract excerpt

The Mi tochondrial contact site and C ristae O rganizing S ystem (MICOS) complex is an inner mitochondrial membrane (IMM) assembly present at the cristae junction. It is responsible for regulating cristae formation and remodeling. However, its structure is not known. We applied Bayesian integrative structure determination to characterize the structure of the Mic60, Mic19, Mic10, and Mic13-containing MICOS comp...

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Literature Corpus work: e1238908-224b-5f2c-a045-59985a3ff262
DOI: 10.64898/2026.07.19.739404

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