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Article

Conserved GxxxG and WN motifs of MIC13 are essential for bridging two MICOS subcomplexes.

Biochimica et biophysica acta. Biomembranes - 1 Dec 2021

Urbach Jennifer, Kondadi Arun Kumar, David Céline, Naha Ritam, Deinert Kim, Reichert Andreas S, Anand Ruchika

Abstract excerpt

Mitochondrial ultrastructure is highly adaptable and undergoes dynamic changes upon physiological and energetic cues. MICOS (mitochondrial contact site and cristae organizing system), a large oligomeric protein complex, maintains mitochondrial ultrastructure as it is required for formation of crista junctions (CJs) and contact sites. MIC13 acts as a critical bridge between two MICOS subcomplexes. Deletion of...

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Identifiers

PMID: 34271005
DOI: 10.1016/j.bbamem.2021.183683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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