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Article

Phospholipid association is essential for dynamin-related protein Mgm1 to function in mitochondrial membrane fusion.

The Journal of biological chemistry - 16 Oct 2009

Rujiviphat Jarungjit, Meglei Gabriela, Rubinstein John L, McQuibban G Angus

Abstract excerpt

Mgm1, the yeast ortholog of mammalian OPA1, is a key component in mitochondrial membrane fusion and is required for maintaining mitochondrial dynamics and morphology. We showed recently that the purified short isoform of Mgm1 (s-Mgm1) possesses GTPase activity, self-assembles into low order oligomers, and interacts specifically with negatively charged phospholipids (Meglei, G., and McQuibban, G. A. (2009)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19703904
DOI: 10.1074/jbc.M109.044933
PMCID: PMC2781412

Genes

OPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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