Article
Genomic profiles and clinical presentation of chordoma.
Acta neuropathologica communications - 12 Aug 2024
Koka Hela, Zhou Weiyin, McMaster Mary L, Bai Jiwei, Luo Wen, Klein Alyssa, Zhang Tongwu, Hua Xing, Li Xin, Wang Difei, Xiong Yujia, Jones Kristine, Vogt Aurelie, Hicks Belynda, Parry Dilys, Goldstein Alisa M, Yang Xiaohong R
Abstract excerpt
Chordoma is a rare bone cancer with variable clinical outcomes. Here, we recruited 184 sporadic chordoma patients from the US and Canada and collected their clinical and treatment data. The average age at diagnosis was 45.5 years (Range 5-78) and the chordoma site distribution was 49.2% clivus, 26.2% spinal, and 24.0% sacral. Most patients (97.5%) received surgery as the primary treatment, among whom 85.3% also...
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