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Article

The mutational landscape of skull base and spinal chordomas and the identification of potential prognostic and theranostic biomarkers

7 Apr 2023

Abstract excerpt

OBJECTIVE: Chordomas are rare bone neoplasms characterized by a high recurrence rate and no benefit from any approved medical treatment to date. However, the investigation of molecular alterations in chordomas could be essential to prognosticate, guide clinical decision-making, and identify theranostic biomarkers. The aim of this study was to provide a detailed genomic landscape of a homogeneous series of 64...

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Identifiers

PMID: 37029667
DOI: 10.3171/2023.1.jns222180

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