Article

Pericytes modulate brain vascular integrity in social stress and depression

2024-10-08

Abstract excerpt

<title>Abstract</title> <p>Major depressive disorder (MDD) is a leading cause of disease burden worldwide with low therapeutic efficacy. The blood-brain barrier (BBB) is essential to maintain brain homeostasis and regulate drug delivery. Chronic social stress, MDD’s main environmental risk factor, is associated with neurovascular pathology in mice including loss of BBB integrity in mood-regulating brain regions i...

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Literature Corpus work: 9a1ce023-7c4e-5d60-8cf6-eaa7bc70e011
DOI: 10.21203/rs.3.rs-5060339/v1

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