Article

Stress-induced dysfunction of neurovascular astrocytes contributes to sex-specific behavioral deficits

2024-05-14

Abstract excerpt

Astrocytes form an integral component of the neurovascular unit, ensheathing brain blood vessels with projections high in aquaporin-4 (AQP4) expression. These AQP4-rich projections facilitate interaction between the vascular endothelium, astrocytes, and neurons, and help stabilize vascular morphology. Studies using preclinical models of psychological stress and post-mortem tissue from patients with major depressiv...

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Literature Corpus work: 6dacaaa4-b2e5-54f2-a256-45daded07ad9
DOI: 10.1101/2024.05.14.594147

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