Pericytes mediate neurovascular remodeling in chronic arterial hypertension

Abstract excerpt

Chronic arterial hypertension restructures the vascular architecture of the brain, leading to a series of pathological responses that culminate in cerebral small vessel disease. Pericytes respond dynamically to vascular challenges; however, how they manifest under the continuous strain of hypertension has not been elucidated. Therefore, in this study, we characterized pericyte behavior alongside hypertensive state...

Topics

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• Cell Plasticity
• Hypertension
• Hypertension, Pulmonary
• Lung
• Pericytes
• Phenotype
• Signal Transduction
• Vascular Remodeling

Identifiers and source

Literature Corpus work

d4b97fe2-b897-5cc0-ae11-34cb37c31ef3

DOI

10.1101/2024.05.13.594041