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The neurovascular extracellular matrix in health and disease

10 Dec 2020

Abstract excerpt

The blood-brain barrier (BBB) is a vital interface that supports normal brain functions. Endothelial cells (ECs) are the main component of the BBB and are highly specialized to govern the transfer of substances into brain. The EC lumen is enmeshed with an extracellular matrix (ECM), known as the endothelial glycocalyx layer (EGL). The lumen-facing EGL is primarily comprised of proteoglycans (PGs) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33302738
DOI: 10.1177/1535370220977195

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