Article

Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse

2024-07-30

Abstract excerpt

Exposure to early life adversity (ELA) poses a significant global public health concern, with profound pathophysiological implications for affected individuals. Studies suggest that ELA contributes to endothelial dysfunction, bringing into question the functional integrity of the neurovascular unit in brain regions vulnerable to chronic stress. Despite the importance of the neurovasculature in maintaining normal b...

Identifiers and source

Literature Corpus work: d41ce6cf-e259-5c67-bfed-5c6cedb0d26a
DOI: 10.1101/2024.07.29.605502

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