Article

Amplified Microglial Dysfunction and Brain Lesions in Mouse Models for Comorbidity of Chronic Stress and Intracerebral Hypoperfusion

2024-03-29

Abstract excerpt

Both clinical and preclinical evidence demonstrates a robust association between mood disorders and cerebrovascular diseases, with the dysfunction of the neurovascular unit (NVU) recognized as a crucial factor. Despite existing research illustrating that chronic stress can induce mood-related behavioral deficits by disrupting the NVU, the underlying mechanisms remain elusive. In this study, we uncovered notable tr...

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Literature Corpus work: 6c3090e3-ed41-5bbd-8375-dbe0e1d29106
DOI: 10.21203/rs.3.rs-4160477/v1

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