Article

Targeted ATAC-see (tATAC-see): A Visual Assay for Target-Specific Chromatin Profiling

2026-07-14

Abstract excerpt

We present targeted ATAC-see (tATAC-see), a visual genomics assay for site-specific chromatin profiling. By integrating the in situ visualization of ATAC-see with antibody-tethered tagmentation, tATAC-see captures chromatin states at defined protein-occupied domains with the simplicity of standard immunofluorescence. Modulating the spatial interaction radius of Tn5 via salt titration enables extended tagmentation...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a01f7ad-9467-554a-a5a7-06d277b87ae6
DOI: 10.64898/2026.07.13.738302

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Targeted ATAC-see (tATAC-see): A Visual Assay for Target-Specific Chromatin ProfilingDOI 10.64898/2026.07.13.738302Read

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing dataSemantic proximity Read

Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clusteringSemantic proximity Read

Integrative epigenomic profiling by high-speed super-resolution imaging and deep learning reveals chromatin state biomarkersSemantic proximity Read

High-throughput Oligopaint screen identifies druggable regulators of genome foldingSemantic proximity Read

Single-molecule Imaging of SWI/SNF Chromatin Remodelers Reveal Multi-modal and Cancer-mutant-specific Landscape of DNA-binding DynamicsSemantic proximity Read

txci-ATAC-seq, a massive-scale single-cell technique to profile chromatin accessibilitySemantic proximity Read

Perturb-tracing enables high-content screening of multiscale 3D genome regulatorsSemantic proximity Read

OptiFoot: a method for recording protein footprints on DNA for microscopy and sequence analysisSemantic proximity Read

Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical ScreenSemantic proximity Read

Spatial-ATAC-seq: spatially resolved chromatin accessibility profiling of tissues at genome scale and cellular levelSemantic proximity Read

In situ chromatin interactomics using a chemical bait and trap approach.Semantic proximity Read

ShinyArchR.UiO: User-friendly, integrative and open-source tool for visualisation of single-cell ATAC-seq data using ArchRSemantic proximity Read