Article

TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ <sub>42</sub> in HMC3 cells

2020-10-08

Abstract excerpt

Alzheimer’s disease (AD) is characterized by the accumulation in the brain of extracellular amyloid β (Aβ) plaques as well as intraneuronal inclusions (neurofibrillary tangles) consisting of total tau and phosphorylated tau. Also present are dystrophic neurites, loss of synapses, neuronal death, and gliosis. AD genetic studies have highlighted the importance of inflammation in this disease by identifying several r...

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Literature Corpus work: 99f64084-2112-54a6-b3de-a7655fde5cd4
DOI: 10.1101/2020.10.08.329938

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