Article

NAD <sup>+</sup> activates renal metabolism and protects from chronic kidney disease in a model of Alport syndrome

2024-02-29

Abstract excerpt

<h4>ABSTRACT</h4> Chronic kidney disease (CKD) is associated with renal metabolic disturbances, including impaired fatty acid oxidation (FAO). Nicotinamide adenine dinucleotide (NAD + ) is a small molecule that participates in hundreds of metabolism-related reactions. NAD + levels are decreased in CKD, and NAD + supplementation is protective. However, both the mechanism of how NAD + supplementation protects f...

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Literature Corpus work: 993a3a44-9963-5218-9a04-b49d995375cc
DOI: 10.1101/2024.02.26.580911

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