Article

Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner

2024-06-27

Abstract excerpt

<h4>SUMMARY</h4> Nicotinamide adenine dinucleotide (NAD) is essential for many enzymatic reactions, including those involved in energy metabolism, DNA repair and the activity of sirtuins, a family of defensive deacylases. During aging, levels of NAD + can decrease by up to 50% in some tissues, the repletion of which provides a range of health benefits in both mice and humans. Whether or not the NAD + precursor...

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Literature Corpus work: b2ef5ab1-7a34-5ec8-a1db-88d72392d8c9
DOI: 10.1101/2024.06.21.599604

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