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The transcriptome of <i>Balamuthia mandrillaris</i> trophozoites for structure-based drug design

2020-06-30

Abstract excerpt

Balamuthia mandrillaris , a pathogenic free-living amoeba (FLA), causes cutaneous skin lesions as well as the brain-eating disease: Balamuthia granulomatous amoebic encephalitis (GAE). These diseases, and diseases caused by other pathogenic FLA, Naegleria fowleri or Acanthamoeba species, are minimally studied from a drug discovery perspective; few targets have been validated or characterized at the molecular le...

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Literature Corpus work
98a4b3c6-6d4c-57ae-a840-abbc82342a93
DOI
10.1101/2020.06.29.178905
Open publication

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