Article

Clinical metagenomic identification of <i>Balamuthia mandrillaris</i> encephalitis and assembly of the draft genome: the critical need for reference strain sequencing

2015-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Primary amoebic meningoencephalitis (PAM) is a rare, often lethal cause of encephalitis, for which early diagnosis and prompt initiation of combination antimicrobials may improve clinical outcomes. In this study, we present the first draft assembly of the Balamuthia mandrillaris genome recovered from a rare survivor of PAM, in total comprising 49 Mb of sequence. Comparative analysis of the mito...

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Literature Corpus work: ea4c5a5e-00da-503a-95fe-4fa26e055103
DOI: 10.1101/024455

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