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Diagnostic Delay, Metagenomic Next-Generation Sequencing and Survival Outcomes in <em>Balamuthia mandrillaris</em> Granulomatous Amoebic Encephalitis: A Systematic Review of Global Case Reports

2026-06-22

Abstract excerpt

<h4>Background: </h4> and Objectives: Balamuthia mandrillaris granulomatous amoebic encephalitis (GAE) is a rare, frequently fatal central nervous system infection in which delayed recognition remains a major determinant of outcome. The increasing use of metagenomic next-generation sequencing (mNGS), plasma microbial cell-free DNA sequencing and targeted sequencing has changed the diagnostic pathway for unexplaine...

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Literature Corpus work
45b60262-890a-5d9a-88f9-0c8b9164c2a9
DOI
10.20944/preprints202606.1579.v1
Open publication

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Diagnostic Delay, Metagenomic Next-Generation Sequencing and Survival Outcomes in <em>Balamuthia mandrillaris</em> Granulomatous Amoebic Encephalitis: A Systematic Review of Global Case ReportsDOI 10.20944/preprints202606.1579.v1
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