Back to search

Article

<i>Naegleria fowleri:</i> protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

2020-10-20

Abstract excerpt

<h4>ABSTRACT</h4> Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform plate to its destination: the brain’s frontal lobes. The amoeba thrives in warm, freshwater environments, with peak infection rates in the summer mo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a1da2473-4fcd-5caf-8ead-9bb024da7e71
DOI
10.1101/2020.10.20.327296
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>Naegleria fowleri:</i> protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoebaDOI 10.1101/2020.10.20.327296
Select a neighboring publication to make it the new centre.