Article
A single helix repression domain is functional across eukaryotes
2022-05-10
Abstract excerpt
The corepressor TOPLESS (TPL) and its paralogs coordinately regulate a large number of genes critical to plant development and immunity. As in many members of the larger pan-eukaryotic Tup1/TLE/Groucho corepressor family, TPL contains a Lis1 Homology domain (LisH), whose function is not well understood. We have previously found that the LisH in TPL—and specifically the N-terminal 18 amino acid alpha-helical region...
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Identifiers and source
- Literature Corpus work
- 988cdad7-ac5c-541b-a44e-b7cb1df008be
- DOI
- 10.1101/2022.05.09.491245
