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Article

A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.

Science advances - 1 Jun 2017

Ma Honglei, Duan Jingbo, Ke Jiyuan, He Yuanzheng, Gu Xin, Xu Ting-Hai, Yu Hong, Wang Yonghong, Brunzelle Joseph S, Jiang Yi, Rothbart Scott B, Xu H Eric, Li Jiayang, Melcher Karsten

Abstract excerpt

TOPLESS are tetrameric plant corepressors of the conserved Tup1/Groucho/TLE (transducin-like enhancer of split) family. We show that they interact through their TOPLESS domains (TPDs) with two functionally important ethylene response factor-associated amphiphilic repression (EAR) motifs of the rice strigolactone signaling repressor D53: the universally conserved EAR-3 and the monocot-specific EAR-2. We present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28630893
DOI: 10.1126/sciadv.1601217
PMCID: PMC5457145

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