Article

Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells

2022-11-10

Abstract excerpt

<h4>SUMMARY</h4> Stiffened arteries are a pathology of atherosclerosis, hypertension, and coronary artery disease and a key risk factor for cardiovascular disease events. The increased stiffness of arteries triggers the hypermigration and hyperproliferation of vascular smooth muscle cells (VSMCs), leading to neointimal hyperplasia and accelerated neointima formation, but the mechanism of this trigger is not known...

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Literature Corpus work: 985af3a1-194a-546c-b6ad-412574b1ddf6
DOI: 10.1101/2022.11.09.515885

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