Article

Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis

2017-10-26

Abstract excerpt

To compensate for accumulating damages and cell death, adult homeostasis (e.g., body fluids and secretion) requires organ regeneration, operated by long-lived stem cells. How stem cells can survive throughout the animal life yet remains poorly understood. Here we show that the transcription factor Shavenbaby (Svb, OvoL in vertebrates) is expressed in renal/nephric stem cells (RNSCs) of Drosophila and required for...

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Literature Corpus work: 98519214-5128-54b7-87eb-287f1b91daae
DOI: 10.1101/163279

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