Article
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control.
Developmental cell - 1 Mar 2008
Zhang Lei, Ren Fangfang, Zhang Qing, Chen Yongbin, Wang Bing, Jiang Jin
Abstract excerpt
The Hippo (Hpo) signaling pathway governs cell growth, proliferation, and apoptosis by controlling key regulatory genes that execute these processes; however, the transcription factor of the pathway has remained elusive. Here we provide evidence that the TEAD/TEF family transcription factor Scalloped (Sd) acts together with the coactivator Yorkie (Yki) to regulate Hpo pathway-responsive genes. Sd and Yki form a...
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