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Article

The Retinoblastoma pathway regulates stem cell proliferation in freshwater planarians.

Developmental biology - 15 Jan 2013

Zhu Shu Jun, Pearson Bret J

Abstract excerpt

Freshwater planarians are flatworms of the Lophotrochozoan superphylum and are well known for their regenerative abilities, which rely on a large population of pluripotent adult stem cells. However, the mechanisms by which planarians maintain a precise population of adult stem cells while balancing proliferation and cell death, remain to be elucidated. Here we have identified, characterized, and functionally...

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Source

Identifiers

PMID: 23123964
DOI: 10.1016/j.ydbio.2012.10.025

Genes

HDAC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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