Article

WNT-driven immune evasion promotes malignant transformation of <i>BRAF</i> -mutant colorectal cancer

2026-01-08

Abstract excerpt

BRAF -mutant colorectal cancer (CRC) constitutes a molecularly and clinically distinct subtype with poor prognosis and resistance to standard therapies, representing a major unmet clinical need. Arising from the serrated pathway of colorectal carcinogenesis rather than the classical adenoma-carcinoma sequence, this subgroup remains relatively understudied yet displays a more aggressive disease course. To investiga...

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Literature Corpus work: 983214d1-4e71-5d26-a2f2-f5207e8e9ec3
DOI: 10.64898/2026.01.07.697968

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