Article

Novel insights into the molecular mechanisms of endocrine resistance in ERα positive breast cancer

2020-01-01

Abstract excerpt

ERα transcriptional activity drives tumour development and metastasis in more than 70% of breast cancer cases. Tamoxifen is the most widely and successfully used endocrine treatment for pre-menopausal women with ERα positive breast cancer. However, subgroups of patients are resistant to this drug. Investigation into the mechanisms of the endocrine refractory phenotype would therefore open possibilities for novel t...

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Literature Corpus work: 97d403c9-6027-5e7f-bbef-1450eedc5115
DOI: 10.17863/cam.66457

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