Endocrine resistance in breast cancer--An overview and update.

Abstract excerpt

Tumors that express detectable levels of the product of the ESR1 gene (estrogen receptor-α; ERα) represent the single largest molecular subtype of breast cancer. More women eventually die from ERα+ breast cancer than from either HER2+ disease (almost half of which also express ERα) and/or from triple negative breast cancer (ERα-negative, progesterone receptor-negative, and HER2-negative). Antiestrogens and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aromatase Inhibitors
• Share to Breast Neoplasms
• Share to Drug Resistance, Neoplasm